发明名称 |
METHOD OF TREATING FUNCTIONAL BOWEL DISORDERS |
摘要 |
The invention relates to a method of treating functional bowel disorders in a subject in need of treatment. The method comprises administering to a subject in need of treatment a therapeutically effective amount of a compound that has 5-HT3 receptor antagonist activity and NorAdrenaline Reuptake Inhibitor (NARI) activity. The invention further relates to a method of treating a functional bowel disorder in a subject in need thereof, comprising coadministering to said subject a first amount of a 5-HT3 antagonist and a second amount of a NARI, wherein the first and second amounts together comprise a therapeutically effective amount or are each present in a therapeutically effective amount. In addition, the method of the invention comprises administering a NARI alone. The functional bowel disorders which can be treated according to the method of the invention include IBS, functional abdominal bloating, functional constipation and functional diarrhea. |
申请公布号 |
WO2004062623(A2) |
申请公布日期 |
2004.07.29 |
申请号 |
WO2004US00807 |
申请日期 |
2004.01.13 |
申请人 |
DYNOGEN PHARMACEUTICALS, INC.;LANDAU, STEVEN, B. |
发明人 |
LANDAU, STEVEN, B. |
分类号 |
A01N43/00;A01N43/54;A61K;A61K31/505;A61K31/519;A61K31/55;A61K31/551;A61K45/06 |
主分类号 |
A01N43/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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