发明名称 |
FUSED HETEROCYCLIC DERIVATIVES AS PPAR MODULATORS |
摘要 |
The present invention is directed to a method of treatment by modulating a peroxisome proliferator activated receptor by employing a compound of Structural Formula (I). The variables in I are defined herein. Also included are compounds, methods of making compounds, and pharmaceutical compositions. The compounds of the present invention are believed to be effective in treating and preventing Syndrome X, Type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, atherosclerosis, and other disorders related to Syndrome X and cardiovascular diseases.
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申请公布号 |
CA2510516(A1) |
申请公布日期 |
2004.07.29 |
申请号 |
CA20032510516 |
申请日期 |
2003.12.31 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
SCHKERYANTZ, JEFFREY MICHAEL;CONNER, SCOTT EUGENE;KNOBELSDORF, JAMES ALLEN;MANTLO, NATHAN BRYAN;ZHU, GUOXIN;WANG, XIAODONG;MAYHUGH, DANIEL RAY |
分类号 |
A61P3/10;A61P29/00;C07D209/10;C07D235/18;C07D263/56;C07D263/57;C07D277/60;C07D277/66;C07D413/12;C07D417/12;C07D471/04;C07D498/04;C07D513/04;(IPC1-7):C07D403/12;C07D405/12;C07D409/12;A61K31/415;A61K31/423;A61K31/427;A61K31/428;A61K31/437;A61K31/55 |
主分类号 |
A61P3/10 |
代理机构 |
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