发明名称 HETEROALKYLAMINO-SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE
摘要 The invention provides compounds represented by the formula:wherein R1, R2, R3, R4, and n are as defined in the Summary of the Invention; and individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.
申请公布号 PL357502(A1) 申请公布日期 2004.07.26
申请号 PL20000357502 申请日期 2000.10.13
申请人 F.HOFFMANN-LA ROCHE AG 发明人 DUNN JAMES PATRICK;FISHER LAWRENCE EMERSON;GOLDSTEIN DAVID MICHAEL;HARRIS WILLIAM;HILL CHRISTOPHER HUW;SMITH JAN EDWARD DAVID;WELCH TERESA ROSANNE
分类号 A61K31/519;A61P1/00;A61P1/04;A61P1/16;A61P3/10;A61P7/00;A61P7/02;A61P7/08;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P11/06;A61P11/08;A61P11/16;A61P13/12;A61P15/08;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P19/06;A61P19/08;A61P19/10;A61P25/00;A61P25/04;A61P25/28;A61P27/02;A61P27/06;A61P27/16;A61P29/00;A61P31/04;A61P31/12;A61P31/16;A61P31/18;A61P33/06;A61P35/00;A61P35/04;A61P37/02;A61P37/04;A61P37/06;A61P43/00;C07D487/04 主分类号 A61K31/519
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