摘要 |
A polymer that is useful for separating plasmid DNA from cell lysates can be dispersed throughout the pores of a porous matrix, forming a chromatographic sorbent. Illustrative of such a polymer is one that comports with the formul a (I): where R1 is C1-6 alkyl; each R2 is independently selected from the grou p consisting of H and C1-6 alkyl, optionally substituted with 1 to 3 OH groups ; R3 is selected from H, C1-14 alkyl, and (C1-14 alkyl)aryl; each n is independently an integer from 1 to 6; a is at least 1; b is at least 1; w is an integer from 0 to 10; and z is at least 1. X is an anion; each Y is independently selected from the group consisting of H, C1-6 alkyl, and a linear homopolymer comprised of monomers, each of them substituted with pendant amines, provided that at least one Y is the linear homopolymer; and "-- ---" represents the remainder of the polymer.
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