发明名称 |
Methods of making indazoles |
摘要 |
Methods of making indazoles are described. The methods involved reacting an aromatic aldehyde with a nitrogen source to form a nitroso aromatic aldehyde. The nitroso aromatic aldehyde is reacted with a reducing agent to form an indazole which ultimately can be used to form desired indazoles which are preferably pharmaceutically active products. The process of the present invention further permits the formation of enantiomerically enriched or pure indazoles such as aminoalkyl indazoles.
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申请公布号 |
US2004142998(A1) |
申请公布日期 |
2004.07.22 |
申请号 |
US20030723297 |
申请日期 |
2003.11.26 |
申请人 |
CONROW RAYMOND E.;DELGADO PETE;DEAN WILLIAM D.;PIERCE DAVID R.;GAINES MICHAEL S. |
发明人 |
CONROW RAYMOND E.;DELGADO PETE;DEAN WILLIAM D.;PIERCE DAVID R.;GAINES MICHAEL S. |
分类号 |
C07D231/56;(IPC1-7):C07D231/56;A61K31/416 |
主分类号 |
C07D231/56 |
代理机构 |
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