发明名称 Methods for modulating effects of radiation in a subject
摘要 The invention features methods and compositions for modulating the effects of radiation in a subject. In one embodiment, the invention features methods for enhancing radiosensitivity of a tumor in an anemic subject by administration of erythropoietin (EPO), particularly a hyperglycosylated EPO isoform such as ARANESP(TM). In general, the invention provides methods for potentiating the effects of radiation therapy in a subject without the need for correction or complete correction of anemia in the subject prior to initiation of radiation therapy. The invention further provides for improved recovery from bone marrow suppression (including non erythroid cell types) and improved overall health of the subject. In another embodiment the invention features methods for treatment of an irradiated subject by accelerating recovery of bone marrow cells (including non-erythroid cell types) in an irradiated subject or mitigating the effects of radiation upon such cells.
申请公布号 US2004132645(A1) 申请公布日期 2004.07.08
申请号 US20030336238 申请日期 2003.01.03
申请人 KNOX SUSAN J.;NING SHOUCHENG 发明人 KNOX SUSAN J.;NING SHOUCHENG
分类号 A61K38/18;(IPC1-7):A61K38/22 主分类号 A61K38/18
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