Assays relating to Toll-like receptor activity

摘要

The present invention provides assays useful for detecting agonists of Toll-like receptors. The assays include, generally, providing a cell culture transfected with a nucleic acid sequence that encodes a reporter operably linked to a TLR-inducible expression control sequence; contacting the cell culture with a test compound; and identifying the compound as a TLR agonist if TLR-inducible expression of the reporter can be detected.