发明名称 Delivery of compounds for the treatment of migraine through an inhalation route
摘要 The present invention relates to the delivery of a migraine headache drug through an inhalation route. Specifically, it relates to aerosols containing a migraine headache drug that are used in inhalation therapy. In a method aspect of the present invention, a migraine headache drug is administered to a patient through an inhalation route. The method comprises: a) heating a composition, wherein the composition a migraine headache drug, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles aerosol comprising particles with less than 5% drug degradation products. In a kit aspect of the present invention, a kit for delivering a migraine headache drug through an inhalation route is provided which comprises: a) a thin coating of an a migraine drug composition and b) a device for dispensing said thin coating as a condensation aerosol.
申请公布号 US2004126328(A1) 申请公布日期 2004.07.01
申请号 US20030735496 申请日期 2003.12.12
申请人 ALEXZA MOLECULAR DELIVERY CORPORATION 发明人 RABINOWITZ JOSHUA D.;ZAFFARONI ALEJANDRO C.
分类号 A61K9/12;A61K9/00;A61K9/72;A61K31/00;A61K31/13;A61K31/137;A61K31/138;A61K31/165;A61K31/167;A61K31/19;A61K31/192;A61K31/216;A61K31/27;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/405;A61K31/407;A61K31/4196;A61K31/421;A61K31/422;A61K31/423;A61K31/437;A61K31/439;A61K31/4402;A61K31/4418;A61K31/4525;A61K31/4545;A61K31/46;A61K31/473;A61K31/48;A61K31/485;A61K31/49;A61K31/495;A61K31/496;A61K31/4985;A61K31/501;A61K31/505;A61K31/519;A61K31/53;A61K31/5415;A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61K45/00;A61K47/48;A61M11/00;A61P15/10;A61P21/02;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/32;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07D471/04;C07D487/04;F24J1/00;(IPC1-7):A61L9/04;A61K9/14;A61K31/554;A61K31/275 主分类号 A61K9/12
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