发明名称 |
RECOMBINANT CELL LINE |
摘要 |
The invention relates to a recombinant cell line capable of inducible expression of an alpha and/or beta subunit of interleukin 12 (IL-12), and an ecdosymeinducible expression vector capable of transfecting a host cell to produce the recombinant cell line of the invention. The invention also relates to a method of screening a candidate compound for the ability to inhibit IL-12 formation and secretion which comprises the steps of incubating a cell line according to the invention with the candidate compound and then assaying the cell line culture for secreted IL-12, or a subunit thereof. |
申请公布号 |
WO2004052929(A2) |
申请公布日期 |
2004.06.24 |
申请号 |
WO2003IB06404 |
申请日期 |
2003.12.08 |
申请人 |
THE QUEEN'S UNIVERSITY OF BELFAST;VANDENBROECK, KOEN;ALLOZA, IRAIDE |
发明人 |
VANDENBROECK, KOEN;ALLOZA, IRAIDE |
分类号 |
A61K38/00;C07K14/54;C12N15/19 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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