发明名称 |
Use of bicyclic esters or amides for the treatment of diseases responsive to enhanced potassium channel activity |
摘要 |
A compound of formula (I): or a salt, solvate or physiologically functional derivative thereof for use as a IK and/or SK channel opener. Methods of screening SK ion channels, particularly SK1 and medicaments for the treatment of a urinogenital, respiratory, cardiovascular, neuronal disorder, of sleeping disorders, sickle cell anemia, pain, inflammation and bowel disease (IBD) are also disclosed.
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申请公布号 |
US2004116405(A1) |
申请公布日期 |
2004.06.17 |
申请号 |
US20030467254 |
申请日期 |
2003.12.16 |
申请人 |
COX BRIAN;CRYAN JENNIFER ELIZABETH;DALE TIMOTHY JAMES;ROBERTSON GRAEME MICHAEL;TREZISE DEREK JOHN |
发明人 |
COX BRIAN;CRYAN JENNIFER ELIZABETH;DALE TIMOTHY JAMES;ROBERTSON GRAEME MICHAEL;TREZISE DEREK JOHN |
分类号 |
G01N33/50;A61K31/165;A61K31/35;A61K31/38;A61K31/44;A61K31/535;A61K45/00;A61P1/04;A61P7/06;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/00;A61P15/00;A61P25/00;A61P25/02;A61P25/18;A61P25/20;A61P29/00;C07C233/11;C07C235/34;C07D215/12;C07D295/185;C07D311/58;C07D335/06;G01N33/15;(IPC1-7):A61K31/537;A61K31/474;C07D413/02 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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