摘要 |
FIELD: organic chemistry, steroids, medicine, pharmacy. SUBSTANCE: invention relates to a new class of 17-acyl-17beta-propinyl steroids of the formula (I) alpha wherein R1 means (CH3)2N-,CH3NH-, NH2-, CH3CO- or CH3S-; R2 means CH3- or CF3-; R3 means hydrogen atom, CH3-, CH3O-, CH3COO-; R4 means hydrogen atom, CH3-, fluorine or chlorine atom; X means oxygen atom that display an anti-progestin activity. EFFECT: valuable medicinal properties of compounds. 12 cl, 2 sch, 3 ex |