| 摘要 |
The present invention aims at providing a therapeutic agent effective for diseases of osteoarthritis and chronic rheumatoid arthritis, and provides a therapeutic agent for osteoarthritis or therapeutic agent for chronic rheumatoid arthritis which contains, as an active ingredient, a chondromodulin-I protein having an activity of growing articular chondrocytes by itself or under coexistence of a basic fibroblast growth factor and an activity of suppressing hyper degradation of cartilage matrix.
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