| 发明名称 |
Humanized antibodies against human 4-1BB |
| 摘要 |
A humanized antibody that binds to human 4-1BB and that allows binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating cancer in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
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| 申请公布号 |
US2004105855(A1) |
申请公布日期 |
2004.06.03 |
| 申请号 |
US20030630406 |
申请日期 |
2003.07.30 |
| 申请人 |
KUNKEL MARIA JURE;GANGULY SUBINAY;ABRAHAM RALPH;HOLLENBAUGH DIANE L.;RILLEMA JILL;THORNE BARBARA;SHUFORD WALTER W.;MITTLER ROBERT S. |
发明人 |
KUNKEL MARIA JURE;GANGULY SUBINAY;ABRAHAM RALPH;HOLLENBAUGH DIANE L.;RILLEMA JILL;THORNE BARBARA;SHUFORD WALTER W.;MITTLER ROBERT S. |
| 分类号 |
A61K;A61K39/395;A61P35/00;C07H21/04;C07K16/28;C12N15/13;C12P21/08;(IPC1-7):C07K16/44;C12Q1/68;C12N5/06 |
主分类号 |
A61K |
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