发明名称 T CELL RECEPTOR DISPLAY
摘要 A proteinaceous particle, for example a bacteriophage, ribosome or cell, displaying on its surface a T-cell receptor (TCR). The displayed TCR is preferably a heterodimer having a non-native disulfide bond between constant domain residues. Such display particles may be used for the creation of diverse TCR libraries for the identificaton of high affinity TCRs. Several high affinities are disclosed.
申请公布号 WO2004044004(A2) 申请公布日期 2004.05.27
申请号 WO2003GB04636 申请日期 2003.10.30
申请人 AVIDEX LIMITED;JAKOBSEN, BENT, KARSTEN;ANDERSEN, TORBEN, BENT;MOLLOY, PETER, EAMON;LI, YI;BOULTER, JONATHAN, MICHAEL 发明人 JAKOBSEN, BENT, KARSTEN;ANDERSEN, TORBEN, BENT;MOLLOY, PETER, EAMON;LI, YI;BOULTER, JONATHAN, MICHAEL
分类号 A61K38/00;C07K14/725;C12N7/00;C12N15/10;C40B40/02 主分类号 A61K38/00
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