摘要 |
FIELD: molecular genetics. SUBSTANCE: invention represents isolated nucleic acid molecule that is hybridized under rigid conditions or shows 80% level of identity with defined genome site located above the encoding segment of FSHbeta gene, and also DNA construction comprising this nucleic acid molecule as a directing sequence for providing the homologous recombination. EFFECT: expanded assortment of genetic therapeutic agents. 18 cl, 12 dwg, 1 tbl |