High surface area, high porosity silica packing with narrow particle and pore diameter distribution and methods of making same

摘要

The present invention relates to LC packing materials in general, and silica-based HPLC packing materials in particular. Methods of forming and using the packing materials are also disclosed. The HPLC packing materials of the present invention feature high surface area and high porosity with good mechanical strength, due in part to the inclusion of a surfactant in the preparation of the LC packing materials. These desirable attributes are due, in part, to the narrow range of pore diameters that are generated in the preparation of the packing material.