| 摘要 |
There is provided amino acid derivatives of formula I, wherein p, q, R<1>, R<2>, R<3>, R<4>, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
|
