| 摘要 |
<p>Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies of conditions involving cancer and the like. The subject invention also relates to processes for making such compounds, as well as to intermediates useful in such processes. 50 claims</p> |
| 申请人 |
AMGEN INC. |
发明人 |
CHEN, GUOQING;ADAMS, JEFFREY;BEMIS, JEAN;CROGHAN, MICHAEL;DIPIETRO, LUCIAN;DOMINGUEZ, CELIA;ELBAUM, DANIEL;GERMAIN, JULIE;HUANG, QI;KIM, JOSEPH L.;OUYANG, XIAOHU;PATEL, VINOD F.;SMITH, LEON M.;TASKER, ANDREW;XI, NING;XU, SHIMIN;YUAN, CHESTER C.;KIM, TAE-SEONG |
