CRYSTALLIZABLE POLYLACTONE COPOLYMER PREPARED BY UTILIZING MONOFUNCTIONAL AND DIFUNCTIONAL POLYMERIZATION INITIATORS

摘要

PROBLEM TO BE SOLVED: To provide an absorbable polylactone copolymer having properties suitable for converting to a transplantable medical device such as a "soft" monofilament suture thread, a composition for producing the same, and a medical device to be prepared therefrom.

SOLUTION: The absorbable polylactone copolymer is prepared in part from about 2 mol% to about 80 mol% glycolide by utilizing a combination of a monofunctional polymerization initiator and a difunctional polymerization initiator to achieve rates of crystallization of the copolymer of at least about two times faster than the rate of crystallization of a copolymer made by a similar process utilizing either the monofunctional or the difunctional polymerization initiator alone. The medical device is prepared by using such a copolymer.

COPYRIGHT: (C)2004,JPO