Radio-labelled ferrite particles and methods for the manufacture and use thereof

摘要

A method for the production of radio-labelled ferrite nanoparticles for use in medical imaging and radiotherapy comprising the steps of: a) adding an aqueous solution containing Fe<2+> and Fe<3+> ions and at least one radioisotope to an alkaline solution and agitating the mixture to form a precipitate comprising ferrite particles labelled with the at least one radioisotope; and b) isolating and washing the precipitated labelled particles, wherein said radioisotope is a radioisotope which functions as a radiotracer isotope and a radiotherapy isotope or said radioisotope includes at least one radiotracer isotope and at least one radiotherapy isotope.