Use of nitric oxide and a device in the therapeutic management of pathogens in mammals

摘要

The present invention relates to a method for the systemic delivery of the nitric oxide moiety either as a dissolved gas or through the administration of nitric oxide donors in an extracorporeal circuit to reduce whole body bacterial contamination by pathogenic or toxic substrates. The utilization of an extracorporeal circuit with the entrainment of nitric oxide is viewed as a novel modality in the medical management of bacteremia (blood poisoning) and/or septicemia in mammals.