摘要 |
The present invention is related to a compound of the formula (I), (II), (III), (IV), (V): wherein Z1, Z2, Z3 and Z4 are each and independently selected from the group comprising C(O)-, -C(S)-, -C(O)-NR10-, -C(S)-NR11-, -C(N-CN)-NR12-, -S(O)-, -S(O2)-, -S(O)-NR13-, and S(O2)-NR14-, -O-, -S- or are each and individually absent; X is a spacer and is independently selected from the group comprising -M1-Ll-K-L2-M2-, wherein Y. is selected from the group comprising alkyl, substituted alkyl, straight alkyl, substituted straight alkyl, branched alkyl, substituted branched alkyl, straight alkenyl, substituted straight alkenyl, branched alkenyl , substituted branched alkenyl, straight alkynyl, substituted straight alkynyl, branched alkynyl, substituted branched alkynyl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, heterocyclyl, substituted heterocyclyl, mono-unsaturated heterocyclyl, poly-unsaturated heterocyclyl, mono-substituted poly-unsaturated heterocyclyl, poly-substituted poly-unsaturated heterocyclyl, mono-substituted mono-unsaturated heterocyclyl, poly-substituted mono-unsaturated heterocyclyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl, wherein Y is different from a peptide or is absent. |
申请人 |
JERINI AG;KNOLLE, JOCHEN;SCHUTKOWSKI, MIKE;HUMMEL, GERD;TRADLER, THOMAS;JOBRON, LAURENCE;CHRISTNER, CLAUDIA;SCHARN, DIRK;STRAGIES, ROLAND;GIBSON, CHRISTOPH;OSTERKAMP, FRANK |
发明人 |
KNOLLE, JOCHEN;SCHUTKOWSKI, MIKE;HUMMEL, GERD;TRADLER, THOMAS;JOBRON, LAURENCE;CHRISTNER, CLAUDIA;SCHARN, DIRK;STRAGIES, ROLAND;GIBSON, CHRISTOPH;OSTERKAMP, FRANK |