发明名称 |
1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES AS CANNABINOID-CB1 RECEPTOR LIGANDS |
摘要 |
The present invention relates to a group of 1H-1,2,4-triazole-3-carboxamide derivatives, to methods for the preparation of these compounds, and to pharmaceutical compositions containing at least one of these compounds as an active ingredient. These 1H-1,2,4-triazole-3-carboxamide derivatives are potent cannabinoid-CB1 receptor agonists, partial agonists, inverse agonists or antagonists, useful for the treatment of disorders involving cannabinoid neurotransmission. The compounds have the general formula (I), wherein R and R1-R3 have the meanings given in the specification.
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申请公布号 |
CA2491394(A1) |
申请公布日期 |
2004.04.01 |
申请号 |
CA20032491394 |
申请日期 |
2003.09.17 |
申请人 |
SOLVAY PHARMACEUTICALS B.V. |
发明人 |
LANGE, JOSEPHUS H.M.;VAN STUIVENBERG, HERMAN H.;KRUSE, CORNELIS G.;MCCREARY, ANDREW C. |
分类号 |
C07D235/00;A61K31/41;A61P25/18;C07D249/10;(IPC1-7):C07D249/10 |
主分类号 |
C07D235/00 |
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