| 发明名称 |
25-HYDROXY-16-ENE-26, 27-BISHOMOCHOLECARCTIFEROLES |
| 摘要 |
The invention relates to a compound of the formula wherein A is Et is ethyl, and R is hydroxy and R1 is hydrogen or =CH2 or R is hydrogen or fluoro and R1 is =CH2. Compounds of formula I stimulate HL-60 cell differentiation. Accordingly, the compounds of formula I are useful as agents for the treatment of neoplastic diseases, such as leukemia. |
| 申请公布号 |
PL186845(B1) |
申请公布日期 |
2004.03.31 |
| 申请号 |
PL19960326837 |
申请日期 |
1996.11.13 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
IACOBELLI JEROME A.;USKOKOVIC MILAN R. |
| 分类号 |
A61K31/59;A61K31/00;A61P35/00;C07C35/32;C07C45/29;C07C45/30;C07C49/513;C07C401/00 |
主分类号 |
A61K31/59 |
| 代理机构 |
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代理人 |
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