Method for producing optically active lactone compounds by using salen cobalt complexes having a cis-beta structure

摘要

A method for producing an optically active lactone compound by Baeyer-Villiger oxidation of a cyclic ketone compound with at least one kind of oxidants selected from the group consisting of hydrogen peroxide and urine-hydrogen peroxide adduct (UHP) using a cobalt(salen) complex having a cis-beta structure expressed by the following formula (I) or (II) as a catalyst.in which X and Y independently denote H, a t-butyl group or an electron-withdrawing substituting group and W is a halogen element.in which X and Y independently denote H, a t-butyl group or an electron-withdrawing substituting group and Z<-> is a monovalent anion. The optically active lactone compounds can be used for the synthesis of medicines and argochemicals.