摘要 |
The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R<1>, R<2>, R<3>, and R<4> are as defined herein. The invention also relates to methods of treating abnormal cell growth, such as cancer, in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1. |
申请人 |
PFIZER PRODUCTS INC.;KATH, JOHN, CHARLES;LYSSIKATOS, JOSEPH, PETER;WANG, HUIFEN, FAYE |
发明人 |
KATH, JOHN, CHARLES;LYSSIKATOS, JOSEPH, PETER;WANG, HUIFEN, FAYE |