| 发明名称 |
EVALUATION METHOD FOR PREDICTING PHARMACOKINETICS OF PM USING LIVER CELLS OF PM OF DRUG METABOLIZING ENZYME CYTOCHROME P450 HAVING A GENETIC POLYMORPH |
| 摘要 |
<p>There is provided a novel evaluation method for predicting the pharmacokinetics of PM using PM liver cells of drug metabolizing enzyme cytochrome P450 having a genetic polymorphism. According to the present invention, the pharmacokinetics (metabolism) of PM can be predicted by using PM liver cells of CYP2D6 among drug metabolizing enzyme cytochrome P450 known to have a genetic polymorphism.</p> |
| 申请公布号 |
WO2004020998(A1) |
申请公布日期 |
2004.03.11 |
| 申请号 |
WO2003IB03802 |
申请日期 |
2003.08.25 |
| 申请人 |
PFIZER PHARMACEUTICALS INC.;SHIMADA, KAORU;TAKASHIMA, TADAYUKI;PFIZER INC. |
发明人 |
SHIMADA, KAORU;TAKASHIMA, TADAYUKI |
| 分类号 |
C12Q1/02;C12Q1/26;(IPC1-7):G01N33/50 |
主分类号 |
C12Q1/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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