发明名称 |
Virus-like particles for the induction of autoantibodies |
摘要 |
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia. |
申请公布号 |
AU770802(B2) |
申请公布日期 |
2004.03.04 |
申请号 |
AU20000012143 |
申请日期 |
1999.10.20 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
JOHN T SCHILLER;BRYCE CHACKERIAN;DOUGLAS R LOWY |
分类号 |
G01N33/564;A61K38/00;A61K39/00;A61K39/12;A61K47/48;A61P29/00;A61P31/12;A61P31/18;C07K14/005;C07K16/08;C07K16/24;C07K16/28;C07K17/00;C07K17/02;C07K19/00;C12N7/04;C12P21/08;G01N33/15;(IPC1-7):A61K47/48;C12N15/00 |
主分类号 |
G01N33/564 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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