MODULATION OF SECONDARY METABOLITE PRODUCTION BY ZINC BINUCLEAR CLUSTER PROTEINS
摘要
Disclosed are methods for the modulation of secondary metabolite production by fungi through genetic manipulation of such fungi. Also disclosed are new commercial processes using ZBC proteins, or variants thereof, to significantly increase useful secondary metabolite production. Generally, the methods according to the invention comprise expressing in a fungus a ZBC protein or a variant thereof.
申请公布号
WO0224865(A3)
申请公布日期
2004.02.26
申请号
WO2001US29288
申请日期
2001.09.19
申请人
MICROBIA, INC.;HOLTZMAN, DOUGLAS;MADDEN, KEVIN;MAXON, MARY;SHERMAN, AMIR
发明人
HOLTZMAN, DOUGLAS;MADDEN, KEVIN;MAXON, MARY;SHERMAN, AMIR