DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1 (OGR-1)

摘要

The invention provides a human OGR-1 which is associated with the disorders of the peripheral and central nervous system, cardiovascular diseases, inflammation, hematological disease and gastro-intestinal diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of disorders of the peripheral and central nervous system, cardiovascular diseases, inflammation, hematological disease and gastro-intestinal diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of OGR-1 as well as pharmaceutical compositions comprising such compounds.