发明名称 |
BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM |
摘要 |
<p>The present invention provides a method for treating diseases caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof an effective amount of a pyrrolo-pyrazole or pyrazolo-azepine. The invention also provides specific pyrrolo-pyrazoles and pyrazolo-azepines, useful intermediates, a library comprising at least two of them, a process for their preparation and the pharmaceutical compositions containing them, which are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, viral infections, autoimmune diseases and neurodegenerative disorders.</p> |
申请公布号 |
WO2004013144(A1) |
申请公布日期 |
2004.02.12 |
申请号 |
WO2003EP07851 |
申请日期 |
2003.07.16 |
申请人 |
PHARMACIA ITALIA SPA;VILLA, MANUELA;ABRATE, FRANCESCA;FANCELLI, DANIELE;VARASI, MARIO;VULPETTI, ANNA |
发明人 |
VILLA, MANUELA;ABRATE, FRANCESCA;FANCELLI, DANIELE;VARASI, MARIO;VULPETTI, ANNA |
分类号 |
A61K45/00;A61K31/415;A61K31/4162;A61K31/5517;A61K45/06;A61P9/00;A61P11/00;A61P13/08;A61P13/12;A61P17/06;A61P19/02;A61P25/28;A61P31/12;A61P35/00;A61P35/04;A61P37/02;A61P43/00;C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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