发明名称 |
PROCESS FOR PRODUCING GLUTATHIONE |
摘要 |
There is disclosed a fermentation process for producing glutathione which comprises (a) the obtainment of a biomass pre-culture by pre-cultivating, in aerobic conditions, a strain of a glutathione producing yeast wherein the glutathione content per biomass unit is higher than 1.2% w/w; (b) the cultivation, in aerobic conditions, of the resulting biomass pre-culture such that the resulting biomass density is higher than 50 g/l; (c) the activation of the cultured biomass; and (d) the recovery of the cultured biomass, extracting glutathione at a pH equal to or lower than 6 and purifying the resulting glutathione. The process allows to obtain glutathione with high yields and relatively low costs.
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申请公布号 |
CA2436682(A1) |
申请公布日期 |
2004.02.09 |
申请号 |
CA20032436682 |
申请日期 |
2003.08.07 |
申请人 |
GNOSIS S.R.L. |
发明人 |
PAGANI, HERMES;BERARDI, ENRICO GIUSEPPE ROBERTO;BENEDETTI, ALBERTO;ROLLINI, MANUELA;MANZONI, MATILDE;NICHELE, MARINA |
分类号 |
C12P21/00;C12P21/02;C12R1/84;(IPC1-7):C12P21/02 |
主分类号 |
C12P21/00 |
代理机构 |
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地址 |
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