摘要 |
<p>The compounds are used in the composition of antiparasitic formulations. They have the formula where R1 is 2,4,6-trisubstituted phenyl or 3,5-disubstituted pyridin-2-yl; R3 is C1-C4 alkyl, optionally substituted by hydroxy or by one or more halo, cyano, alkanoyl or phenyl; R5 is hydrogen, C1-C4 alkyl, amino or halo; R2 and R4 are independant from each other and individually mean hydrogen, C1-C4 alkyl, fluoro, chloro or bromo, or together with the carbon atom to which they are bound form C3-C6 cycloalkyl group; R6 & R8, independent from each other and individually mean hydrogen, C1-C4 alkyl, fluoro, chloro or bromo, or when R2 & R4 do not form part of a cycloalkyl group R2 & R4 together with the carbon atoms to which they are bound can form C5-C7 cycloalkyl group; and R7 is hydrogen, C1-C4 alkyl, optionally substituted by one or more halo, or C1-C- alkoxy. The invention also relates to their pharmaceutically, veterinary or agriculturally acceptable salts or solvates. 24 claims</p> |