| 发明名称 |
Dimer-selective RXR modulators and methods for their use |
| 摘要 |
Dimer-selective RXR modulator compounds having agonist, partial agonist and/or antagonist activity in the context of an RXR homodimer and/or RXR heterodimers are provided. Also provided are pharmaceutical compositions incorporating such dimer-selective RXR modulator compounds and methods for their therapeutic use.
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| 申请公布号 |
US2004019072(A1) |
申请公布日期 |
2004.01.29 |
| 申请号 |
US20030360580 |
申请日期 |
2003.02.05 |
| 申请人 |
CANAN-KOCH STACIE;HWANG CHAN K.;BOEHM MARCUS F.;BADEA BETH ANN;DARDASHTI LAURA J.;ZHANG LIN;NADZAN ALEX M.;HEYMAN RICHARD A.;MUKHERJEE RANJAN;LALA DEEPAK S.;FARMER LUC J. |
发明人 |
CANAN-KOCH STACIE;HWANG CHAN K.;BOEHM MARCUS F.;BADEA BETH ANN;DARDASHTI LAURA J.;ZHANG LIN;NADZAN ALEX M.;HEYMAN RICHARD A.;MUKHERJEE RANJAN;LALA DEEPAK S.;FARMER LUC J. |
| 分类号 |
A61K9/00;A61K9/02;A61K31/19;A61K31/192;A61K31/201;A61K31/202;A61K31/235;A61K31/352;A61K31/357;A61K31/425;A61K31/435;A61K31/44;A61K31/4418;A61K31/473;A61K31/538;A61K38/28;A61K45/06;A61P3/04;A61P3/10;A61P5/06;A61P5/10;A61P9/00;A61P17/00;A61P17/02;A61P17/14;A61P25/00;A61P27/02;A61P29/00;A61P31/12;A61P35/00;A61P37/02;A61P43/00;C07C49/453;C07C57/50;C07C59/64;C07C59/66;C07C59/72;C07C63/49;C07C63/66;C07C65/17;C07C65/26;C07C65/28;C07C65/36;C07C65/40;C07C69/734;C07C69/76;C07C233/00;C07C251/48;C07C311/49;C07D213/00;C07D221/08;C07D257/00;C07D265/34;C07D303/00;C07D311/92;C07D317/30;C07D333/00;(IPC1-7):C07D221/22;C07C63/44;A61K31/195;A61K31/198 |
主分类号 |
A61K9/00 |
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