发明名称 |
Specific inhibitors of hyaluronidase 2, and methods of identifying and using same |
摘要 |
Methods for identifying a hyaluronidase 2 (HYAL2) specific inhibitor, which selectively inhibits HYAL2 activity, but does not substantially affect the activity of non-inflammatory hyaluronidases, are provided. Also provided are HYAL2 specific inhibitors obtained using such a method. In addition, methods for ameliorating an inflammatory disorder or vasculitis condition by specifically inhibiting HYAL2 is provided.
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申请公布号 |
US6682904(B1) |
申请公布日期 |
2004.01.27 |
申请号 |
US20020222032 |
申请日期 |
2002.08.15 |
申请人 |
DELIATROPH PHARMACEUTICALS, INC. |
发明人 |
FROST GREGORY I. |
分类号 |
A61K38/00;C12N9/26;C12Q1/34;(IPC1-7):C12Q1/34;C12Q1/00;C12Q1/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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