Novel chemo-enzymatic process for the preparation of opticaly enriched beta-benzyl-gamma-butyrolactones

摘要

The present invention relates to a novel process for the preparation of optically enriched substituted R(+)beta-benzyl-gamma-butyrolactones of the general formula 1, wherein, R1 and R2 independently represent the following groups, R1=R2=H, OH, -OCnH2n+1 (n=1 to 8), NH2, and/or CF3, R1 and R2 together represents -O(CH2)mO- where m=2 to 4.