发明名称 |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase |
摘要 |
This invention relates to the modulation and/or inhibition of cell signaling, cell proliferation, cell inflammatory response, the control of abnormal cell growth and cell reproduction. More specifically, this invention relates to the use of mono- and/or bicyclic aryl or heteroaryl quinazoline compounds in inhibiting cell proliferation, including compounds which are useful protein tyrosine kinase (PTK) inhibitors. The method of treating cell proliferation and/or differentiation or mediator release using said quinazoline compounds and their use in pharmaceutical compositions is described.
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申请公布号 |
US2004014774(A1) |
申请公布日期 |
2004.01.22 |
申请号 |
US20030617342 |
申请日期 |
2003.07.10 |
申请人 |
MYERS MICHAEL R.;SPADA ALFRED P.;MAGUIRE MARTIN P.;PERSONS PAUL E.;ZILBERSTEIN ASHER;HSU CHIN-YI JENNY;JOHNSON SUSAN E. |
发明人 |
MYERS MICHAEL R.;SPADA ALFRED P.;MAGUIRE MARTIN P.;PERSONS PAUL E.;ZILBERSTEIN ASHER;HSU CHIN-YI JENNY;JOHNSON SUSAN E. |
分类号 |
A61K31/517;A61K31/5377;C07C43/205;C07C43/225;C07C43/23;C07D213/30;C07D213/64;C07D215/14;C07D215/18;C07D215/20;C07D215/22;C07D215/233;C07D215/50;C07D239/74;C07D239/88;C07D239/91;C07D239/93;C07D239/94;C07D241/42;C07D241/52;C07D265/22;C07D277/64;C07D401/04;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D471/04;(IPC1-7):A61K31/541;A61K31/537 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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地址 |
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