发明名称 |
Identification of compounds which stimulate bone formation using a cell-based screening assay targeting BMP signaling |
摘要 |
Methods and compositions for measuring the effects of molecules which stimulate BMP and Cbfa1 signaling are disclosed, wherein the response elements in the Smad family and Cbfa1 are utilized in an assay system to modulate the production of an assayable product of a reporter construct.
|
申请公布号 |
US2004009511(A1) |
申请公布日期 |
2004.01.15 |
申请号 |
US20030423262 |
申请日期 |
2003.04.24 |
申请人 |
MUNDY GREGORY R.;CHEN DI;ZHAO MING |
发明人 |
MUNDY GREGORY R.;CHEN DI;ZHAO MING |
分类号 |
C07K14/47;C07K14/51;(IPC1-7):C12Q1/68;C07H21/04;C07K14/705;C12P21/02;C12N5/06 |
主分类号 |
C07K14/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|