摘要 |
PROBLEM TO BE SOLVED: To provide a treating or preventive medicinal composition for injury treatable or preventable with an antispasmodic. SOLUTION: The therapeutic activity is obtained by a compound represented by formula (1), wherein Y is CR<SB>1</SB>, R<SB>1</SB>is cyano or the like, R<SB>2</SB>and R<SB>9</SB>are H, R<SB>3</SB>and R<SB>4</SB>are a 1-4C alkyl, R<SB>5</SB>is hydroxy, R<SB>6</SB>is a 1-2C alkyl, R<SB>7</SB>is fluorophenyl, R<SB>8</SB>is H or a 1-6C alkyl and R<SB>8</SB>-N-CO-R<SB>7</SB>is positioned at trans site to R<SB>5</SB>. COPYRIGHT: (C)2004,JPO
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