发明名称 |
Tissue factor protein variants |
摘要 |
The invention provides amino acid sequence variants of tissue factor protein. The tissue factor protein variants have a greater affinity for Factor VII/VIIa than wild-type counterparts. The invention also provides pharmaceutical compositions comprising the novel compositions as well as their use in diagnostic, therapeutic, and prophylactic methods.
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申请公布号 |
US2004006217(A1) |
申请公布日期 |
2004.01.08 |
申请号 |
US20030427643 |
申请日期 |
2003.04.30 |
申请人 |
GENENTECH, INC. |
发明人 |
KELLEY ROBERT F.;LEE GEOFFREY F. |
分类号 |
C12N15/09;A61K38/00;A61K38/36;A61P7/02;C07K14/705;C07K14/745;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;(IPC1-7):A61K38/18;C07K14/475 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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