| 摘要 |
The present invention provides a single-use electronic device and test card for use therein which performs a coagulation or lysis assay of a blood or plasma sample. The device includes a housing having an exterior surface and defining an interior area and means for receiving the sample through the housing into the interior space. A non-porous substrate is positioned within the interior space for receiving the sample thereon. Preferably, a reagent accelerates the coagulation of the sample and is positioned on the substrate and in contact with the sample. An electroactive species is added to the sample. The device also measures the impedance of the sample and generating an electrical signal which correlates to a curve of the coagulation/lysis assay. Optionally, the electrical signal is received and converted into a digital output corresponding to the coagulation/lysis assay using assay calibration information stored therein. The digital output can be displayed external to the housing. A method of determining the coagulation or lysis of a sample provides for measuring the impedance of the sample and generating an electrical signal which correlates to a curve of the coagulation/lysis assay.
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