发明名称 |
Synthesis of spiro esters, spiro ortho carbonates, and intermediates |
摘要 |
Ortho esters and ortho carbonates can be produced by alkylating esters and carbonates with, for example, the hexafluorophosphate salt of a trialkyl oxonium ion. The spiro species are useful intermediates in the synthesis of complex organic molecules. Synthetic pathways for the production of medically active compounds incorporates spiro ortho esters. Anti-first-pass effect materials are produced in high yield utilizing a synthetic strategy incorporating cyclic ortho ester intermediates.
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申请公布号 |
US2004002611(A1) |
申请公布日期 |
2004.01.01 |
申请号 |
US20030434361 |
申请日期 |
2003.05.09 |
申请人 |
BIOAVAILABILITY SYSTEMS, LLC |
发明人 |
SEEMAYER ROBERT;LIANG JACK |
分类号 |
C07D493/04;C07D493/10;C07D493/20;C07D519/00;(IPC1-7):C07D317/08;C07D493/12 |
主分类号 |
C07D493/04 |
代理机构 |
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地址 |
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