发明名称 |
Host derived proteins binding HCV: medical, diagnostic and purification use |
摘要 |
The finding that the human proteins annexin V, tubulin and apolipoprotein B bind to the hepatitis C virus envelope proteins E1 and/or E2 and the usage of these human proteins to diagnose and treat an infection with hepatitis C virus are described. The usage of the latter proteins to enrich HCV envelope proteins and molecules which inhibit binding of HCV to these human proteins, as well as vaccines employing the E1 and/or E2 binding domains are also disclosed.
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申请公布号 |
US6670114(B1) |
申请公布日期 |
2003.12.30 |
申请号 |
US20000564951 |
申请日期 |
2000.05.05 |
申请人 |
N.V. INNOGENETICS |
发明人 |
MAERTENS GEERT;DEPLA ERIK |
分类号 |
G01N33/53;A61K38/00;A61K38/17;A61K39/00;A61K39/29;A61L2/00;A61L2/16;A61P31/20;C07K1/22;C07K14/18;C07K14/47;C07K14/775;C12N7/00;G01N33/50;G01N33/569;G01N33/576;(IPC1-7):C12Q1/70 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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