发明名称 A METHOD FOR SIMULTANEOUS PRODUCTION OF MULTIPLE PROTEINS; VECTORS AND CELLS FOR USE THEREIN
摘要 <p num="1"><br/><br/><br/>The present invention relates to a method for improving expression of two or <br/>more proteins in a <br/>(host) cell. The method is suited for production of for example recombinant <br/>antibodies that can <br/>be used in a pharmaceutical preparation or as a diagnostic tool. In one <br/>embodiment, the invention <br/>provides a method for obtaining a cell which expresses two or more proteins <br/>comprising <br/>providing said cell with two or more protein expression units encoding said <br/>two or more <br/>proteins, characterised in that at least two of said protein expression units <br/>comprise at least one <br/>STAR sequence wherin said STAR sequence protects said transgenes from the <br/>effect of gene <br/>silencing.<br/>
申请公布号 CA2723500(A1) 申请公布日期 2003.12.24
申请号 CA20032723500 申请日期 2003.06.13
申请人 CHROMAGENICS B.V. 发明人
分类号 C12N15/09;C12N15/79;C07H21/04;C07K16/00;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/00;C12N15/11;C12N15/67;C12N15/82;C12N15/85;C12N15/90;C12P21/02;C12Q1/02;C12Q1/68 主分类号 C12N15/09
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