发明名称 STABILIZED LIQUID ANTI-RSV ANTIBODY FORMULATIONS
摘要 <p>The present invention provides liquid formulations of SYNAGIS® or an antigen­binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS® or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention.</p>
申请公布号 WO2003105894(P1) 申请公布日期 2003.12.24
申请号 US2003018913 申请日期 2003.06.16
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