摘要 |
It is intended to provide remedies for liver diseases, in particular, via the inhibition of the occurrence of portal vein tumor infiltration (PVI). Thus, excellent remedies/preventives for liver diseases containing menatetrenone as the active ingredient are disclosed. These remedies/preventives are efficacious liver cancer, in particular, des-gamma-carboxy prothrombin (DCP) positive liver cancer. Moreover, these remedies/preventives containing menatetrenone as the active ingredient show a remarkable effect of improving the prognosis after the treatment of liver cancer and, exhibit an excellent effect as preventives for liver cancer recurrence.
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申请人 |
EISAI CO., LTD. |
发明人 |
KOIKE, YUKIHIRO;SHIRATORI, YASUSHI;SHIINA, SHUICHIRO;TERATANI, TAKUMA;OBI, SHUNTARO;SATO, SHINPEI;HAMAMURA, KEISUKE;AKAMATSU, MASATOSHI;TATEISHI, RYOSUKE;FUJISHIMA, TOMONORI;KANDA, MIHO;YOSHIDA, HARUHIKO;ISHIKAWA, TAKASHI;KAWASE, TATEO;OMATA, MASAO;MIZUTA, TOSHIHIKO;YASUTAKE, TSUTOMU;EGUCHI, YUICHIRO;FUJIMOTO, MASARU;OZAKI, IWATA;WADA, IKUKO;YAMAMOTO, KYOSUKE |