Compounds and methods for treatment and diagnosis of chlamydial infection

摘要

Isolated polypeptide compounds comprising an immunogenic portion of a Chlamydial antigen for treating Chlamydial infections are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.