发明名称 NITROSODIPHENYLAMINE DERIVATIVES, COMPOSITIONS COMPRISING THEM, AND THE USE THEREOF AS ANTIOXIDANTS AND SPONTANEOUS NITRIC OXIDE DONORS
摘要 The invention relates to compounds of the general formula (I) in which R i, A, n, B and Z are as defined in Claim 1. These compounds can be used for the preparation of antioxidant medicinal products that function as free-radical scavengers or are useful in the treatment of pathologies characterised by an oxidative stress condition and a lack of availability of endothelial nitrogen monoxide. The invention also relates to the pharmaceutical compositions comprising them.
申请公布号 WO03103567(A2) 申请公布日期 2003.12.18
申请号 WO2003EP04919 申请日期 2003.05.12
申请人 MERCK PATENT GMBH;LARDY, CLAUDE;GUEDAT, PHILIPPE;BERARD, ISABELLE;CAPUTO, LIDIA 发明人 LARDY, CLAUDE;GUEDAT, PHILIPPE;BERARD, ISABELLE;CAPUTO, LIDIA
分类号 A61P39/00;A61P39/06;C07D207/09;C07D213/40;C07D213/53;C07D233/54;C07D233/58;C07D233/64;C07D295/13;C07D295/135;C07D453/02 主分类号 A61P39/00
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