发明名称 |
NITROSODIPHENYLAMINE DERIVATIVES, COMPOSITIONS COMPRISING THEM, AND THE USE THEREOF AS ANTIOXIDANTS AND SPONTANEOUS NITRIC OXIDE DONORS |
摘要 |
The invention relates to compounds of the general formula (I) in which R i, A, n, B and Z are as defined in Claim 1. These compounds can be used for the preparation of antioxidant medicinal products that function as free-radical scavengers or are useful in the treatment of pathologies characterised by an oxidative stress condition and a lack of availability of endothelial nitrogen monoxide. The invention also relates to the pharmaceutical compositions comprising them. |
申请公布号 |
WO03103567(A2) |
申请公布日期 |
2003.12.18 |
申请号 |
WO2003EP04919 |
申请日期 |
2003.05.12 |
申请人 |
MERCK PATENT GMBH;LARDY, CLAUDE;GUEDAT, PHILIPPE;BERARD, ISABELLE;CAPUTO, LIDIA |
发明人 |
LARDY, CLAUDE;GUEDAT, PHILIPPE;BERARD, ISABELLE;CAPUTO, LIDIA |
分类号 |
A61P39/00;A61P39/06;C07D207/09;C07D213/40;C07D213/53;C07D233/54;C07D233/58;C07D233/64;C07D295/13;C07D295/135;C07D453/02 |
主分类号 |
A61P39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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