发明名称 BASIC NON-PEPTIDE BRADYKININ ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREFROM
摘要 Non-peptide compounds of formula (I) having activity as specific antagonists of bradykinin (BK) B2 receptor. The compounds are chemically characterized b y the presence of an alpha, alpha-disubstituted amino acid at least one amino group, free or salified, or the corresponding ammonium quaternary salt. Thes e BK receptor antagonists are a novel class of medicaments which can be used i n all the disorders in which said receptors are involved.
申请公布号 CA2488565(A1) 申请公布日期 2003.12.18
申请号 CA20032488565 申请日期 2003.06.05
申请人 MENARINI RICERCHE S.P.A. 发明人 MAGGI, CARLO ALBERTO;CATRAMBONE, FERNANDO;GIOLITTI, ALESSANDRO;TERRACCIANO, ROSA;FINCHAM, CHRISTOPHER INGO;FELICETTI, PATRIZIA;QUARTARA, LAURA;ROSSI, CRISTINA;CALVANI, FEDERICO
分类号 A61K31/47;A61K31/4709;A61K31/496;A61P1/04;A61P1/16;A61P9/00;A61P9/02;A61P9/10;A61P11/00;A61P11/06;A61P13/10;A61P13/12;A61P17/00;A61P17/06;A61P17/14;A61P19/02;A61P25/04;A61P29/00;A61P31/04;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07D215/26;C07D401/12;(IPC1-7):C07D401/14 主分类号 A61K31/47
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