发明名称 Antisense modulation of IL-1 receptor-associated kinase-1 expression
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of IL-1 receptor-associated kinase-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding IL-1 receptor-associated kinase-1. Methods of using these compounds for modulation of IL-1 receptor-associated kinase-1 expression and for treatment of diseases associated with expression of IL-1 receptor-associated kinase-1 are provided.
申请公布号 US2003228690(A1) 申请公布日期 2003.12.11
申请号 US20020167034 申请日期 2002.06.10
申请人 ISIS PHARMACEUTICALS INC. 发明人 BAKER BRENDA F.;FREIER SUSAN M.;DOBIE KENNETH W.
分类号 A61K38/00;C12N15/113;(IPC1-7):A61K48/00;C07H21/04 主分类号 A61K38/00
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